Alpha Brain isn't just any supplement; it's a meticulously crafted formula designed from the ground up by Onnit's team of experts who have dived deep into cognitive science and the benefits of nootropic ingredients. Just like our heart, lungs, and muscles need proper nutrients, our brain craves its own special blend of sustenance to remain sharp and robust. Alpha BRAIN® is like a feast for your mind, packed with everything it needs to boost memory, focus, and overall cognitive function. Engineered by the experts at Onnit, Alpha Brain features three proprietary blends that work synergistically to elevate your brainpower. The Onnit Flow blend is a product, designed to increase alpha wave production, putting your brain into a state of peak performance. Next up is the Onnit Focus blend, which helps your body produce and sustain acetylcholine-a vital neurotransmitter known to enhance focus and memory. Finally, the Onnit Fuel blend promotes a healthy brain environment by optimizing nervous system communication and boosting neurotransmitter activity. With Alpha Brain, you're not just taking a supplement; you're investing in a sharper, more focused you!
This was our key design criteria. A cascade of events and processes supports each outcome. For example, to improve memory, it is necessary to support acetylcholine signaling, but memory also requires proper glutamatergic signaling, synaptic plasticity, long-term potentiation (LTP) and intracellular signaling. Likewise, to improve focus, motivation and emotional resilience, dopamine signaling must be supported. We know that none of these signaling systems exists in isolation-they are all influenced by proper neuroendocrine function. And, they are affected by things outside the brain-the bloodstream (and organs that cleanse it), the endocrine (i.e., hormonal) system, the gut-brain axis, and more. So, we want to consider all of these pathways in the design process, but we want to do so in a way that acknowledges their interconnectedness and interdependence (i.e., a complex systems focus). Neurochemistry is important, but it isn’t something that works or exists in isolation. Peak brain performance requires optimal structure (and restructuring capacity).
This means supporting neurogenesis, synaptogenesis, cell membrane assembly, and myelination. Neurochemical signaling processes, as well as cellular maintenance functions, requires energy. This means supporting cellular energy production and mitochondrial function (i.e., the energy-producing parts of our cells). Optimal energy production requires an adequate supply of oxygen and nutrients, and the ability to remove and/or neutralize byproducts of metabolism, including oxidative and inflammatory molecules. Delivery and removal are done via the blood (i.e., cerebral blood flow), and protection means supporting detoxification, antioxidant and anti-inflammatory systems. While designing our Qualia nootropic formulations, we knew that to sustain our major outcome goals, we had to support all of these entwined processes. Delivering on these goals required a meta-system approach. It required seeking to more thoroughly understand the physiological systems and pathways, as well as their key regulatory points, underlying each cognitive, executive, or emotional process we wanted to support. It required understanding how those physiologic pathways self-regulate and help regulate each other, and where pathways can become bottlenecked (i.e., rate-limiting steps) or lose adaptive capacity, and how they can be supported to function more optimally.
By understanding the intricacies and mutual dependence of physiological processes and pathways, we determined which steps we should nurture. Then, we undertook a comprehensive survey of ingredients known to affect those pathways, reviewed the scientific literature to understand primary and secondary mechanisms of action, along with pharmacodynamics, kinetics, and more. We were able to make educated choices of ingredients which could help sustain the dynamics of each pathway, by targeting multiple steps of a pathway, with special emphasis on rate-limiting steps. While choosing from the multitude of ingredients that could serve our purpose, we took into account how a set of ingredients, as a whole, would support (1) each physiological outcome we wanted to promote, (2) cognitive and subjective outcomes we sought to enhance, and (3) overall general and gamma brainwaves adaptive effects on the rest of the body. Two general design principles of our formulation approach are: (1) each ingredient should serve multiple important functions, and (2) each function should be served by multiple ingredients.